-
Mental Change, Cardiovascular Depression and QT Prolongation Caused by Severe Hypermagnesemia: A Case Report
-
Hyung Oh Choi, Seung Geun Lee, Pil Hyung Lee, Sung Nam Lim, Byeong Seok Sohn, Yun Hee Chung, Gi Byoung Nam
-
Korean J Crit Care Med. 2008;23(2):102-105.
-
DOI: https://doi.org/10.4266/kjccm.2008.23.2.102
-
-
3,404
View
-
19
Download
-
2
Crossref
-
 Abstract
 PDF
- A 50-year-old woman was referred to our hospital for evaluation of mental change and general weakness accompanied by an irregular and weak pulse. She had previously been diagnosed with Bartter's syndrome and had taken potassium-sparing diuretics. She had developed constipation that had led to abdominal pain and had taken excessive magnesium oxide over a long time. On admission, she was lethargic. Her blood pressure (BP) was 130/74 mmHg, with a heart rate varying from 30 to 78 beats/min. An electrocardiogram (ECG) revealed several abnormalities, including first degree AV block, QT prolongation, sinus pause with a junctional rhythm, and paroxysmal tachycardia alternating with sinus pause. Her serum concentration of magnesium was markedly elevated to 16.19 mg/dl. Hemodialysis and a calcium gluconate infusion was attempted to reduce magnesium levels and to counteract the cardiovascular effect of magnesium. As magnesium levels declined, her general medical condition improved and her ECG changes were normalized. Severe hypermagnesemia should be suspected as the cause of mental change, cardiovascular dysfunction, and variable ECG changes.
-
Citations
Citations to this article as recorded by  - An unusual presentation of severe preeclampsia presenting with maternal collapse in the post-cesarean section secondary to drug toxicity associated with pituitary hemorrhage: a case report
Krishna Mylavarapu Kumar, Shyam Madabushi, Amit Lall, Pranjali D. Dwivedi
Ain-Shams Journal of Anesthesiology.2023;[Epub] CrossRef - Symptomatic Hypermagnesemia in Normal Kidney Function with a Colonic Cleansing Agent
Taehong Kim, Tae Hyung Kim, Won Hyuk Lee, Yoo Jin Lee, Sihyung Park, Bong Soo Park, Yang Wook Kim
The Korean Journal of Medicine.2016; 91(3): 306. CrossRef
-
A Case of Stress Cardiomyopathy Complicated by Torsades de Pointes in a Patient with Acute Colitis: A Case Report
-
Hyoungyoung Kim, Gi Byoung Nam, Sang Jin Lee, Hyun Kee Lee, Yoonki Hong, Kee Joon Choi, You Ho Kim
-
Korean J Crit Care Med. 2007;22(2):101-105.
-
-
-
Abstract
PDF
- A 67-year old woman, hospitalized for the management of infectious colitis, developed acute congestive heart failure. Two-dimensional echocardiography revealed left ventricular apical akinesia (ballooning) and basal hyperkinesis, which was compatible with stress cardiomyopathy. A marked QT prolongation and T wave inversion followed by nonsustained polymorphic ventricular tachycardia was noted in the electrocardiogram. Intravenous administration of magnesium completely suppressed the ventricular tachycardia. After recovery from the colitis, the follow-up ECG and echocardiogram were normalized. There was no evidence of ischemic heart disease in the coronary angiography or perfusion scan. Takotsubo cardiomyopathy is one of the most important causes of acquired QT prolongation in ICU (intensive care unit) patients.. A careful monitoring of the QT interval in these patients is warranted particularly when drugs causing QT prolongation are used.
|
KSCCM
